Param | Value | Units | Biological Interpretation |
a | 864 | glucose production rate by liver when G = 0 | |
b | 1.44 | glucose clearance rate independent of insulin | |
c | 0.72 | insulin induced glucose uptake rate | |
d | 43.2 | β-cell maximum insulin secretory rate | |
e | 20,000 | gives inflection point of sigmoidal function | |
f | 432 | whole body insulin clearance rate | |
g | 0.06 | β-cell natural death rate | |
h | 0.84e-3 | determines β-cell glucose tolerance range | |
i | 0.24e-5 | determines β-cell glucose tolerance range | |
K | 900 | Environmental capacity | |
r | 0.01 | growth rate of β-cells | |
α | 0.01 | inverse of half saturation constant |